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Last year, S-Town blew our minds by taking a novelistic approach to its fascinating characters, plot, and setting. This year, playwrights and journalists came out from behind the page in droves. Podcasts are now regularly adapted for television (Homecoming, 2 Dope Queens, Pod Save America, and Dirty John, to name a few). They became more niche and even self-referential: The Onion’s A Very Fatal Murder satirizes true-crime podcasts. There’s even a podcast (Before It Had a Theme) about a radio show that is now also a podcast (This American Life). Podcasts, it seems, are the new black hole (a concept that’s explained very well on HumaNature), because they feed and feed on whatever is around them.
Kidney damage from diabetes is called diabetic nephropathy. The onset of kidney disease and its progression is extremely variable. Initially, diseased small blood vessels in the kidneys cause the leakage of protein in the urine. Later on, the kidneys lose their ability to cleanse and filter blood. The accumulation of toxic waste products in the blood leads to the need for dialysis. Dialysis involves using a machine that serves the function of the kidney by filtering and cleaning the blood. In patients who do not want to undergo chronic dialysis, kidney transplantation can be considered.
I am very excited by the closed-loop artificial pancreas trial which is now in its final stages. Professor Roman Hovorka at the University of Cambridge is currently perfecting an algorithm that enables a continuous glucose monitor and an insulin pump to talk to each other, and take over the delivery of insulin throughout the day and night, to keep glucose levels in range.
There are major barriers for widespread use of islet also-transplantation that can help people with type 1 diabetes. The shortage of islets from donors is a huge obstacle. The other obstacle is that this is still considered an experimental procedure and until the procedure is considered successful enough to be labeled therapeutic by the FDA instead of experimental, the costs of these transplants come from limited research funds.
Many drugs can help calm down overactive pain nerves. These include antiseizure medicines such as gabapentin (brand name Neurontin) and pregabalin (Lyrica). Since seizures are the most obvious case of oversensitive nerves, it makes sense that seizure drugs might help chronic pain. Lyrica seems to have fewer side effects than Neurontin and another drug, Topamax, which often cause mental fogginess.
Glucagon is a hormone that causes the release of glucose from the liver (for example, it promotes gluconeogenesis). Glucagon can be lifesaving and every patient with diabetes who has a history of hypoglycemia (particularly those on insulin) should have a glucagon kit. Families and friends of those with diabetes need to be taught how to administer glucagon, since obviously the patients will not be able to do it themselves in an emergency situation. Another lifesaving device that should be mentioned is very simple; a medic-alert bracelet should be worn by all patients with diabetes.
In countries using a general practitioner system, such as the United Kingdom, care may take place mainly outside hospitals, with hospital-based specialist care used only in case of complications, difficult blood sugar control, or research projects. In other circumstances, general practitioners and specialists share care in a team approach. Home telehealth support can be an effective management technique.
People with type 2 diabetes have insulin resistance, which means the body cannot use insulin properly to help glucose get into the cells. In people with type 2 diabetes, insulin doesn’t work well in muscle, fat, and other tissues, so your pancreas (the organ that makes insulin) starts to put out a lot more of it to try and compensate. "This results in high insulin levels in the body,” says Fernando Ovalle, MD, director of the multidisciplinary diabetes clinic at the University of Alabama in Birmingham. This insulin level sends signals to the brain that your body is hungry.
According to the Mayo Clinic, doctors may use other tests to diagnose diabetes. For example, they may conduct a fasting blood glucose test, which is a blood glucose test done after a night of fasting. While a fasting blood sugar level of less than 100 milligrams per deciliter (mg/dL) is normal, one that is between 100 to 125 mg/dL signals prediabetes, and a reading that reaches 126 mg/dL on two separate occasions means you have diabetes.
Some risks of the keto diet include low blood sugar, negative medication interactions, and nutrient deficiencies. (People who should avoid the keto diet include those with kidney damage or disease, women who are pregnant or breast-feeding, and those with or at a heightened risk for heart disease due to high blood pressure, high cholesterol, or family history. (40)
2018 was a year whose realities sometimes seemed to approach the dystopias and dramas of fiction, as stories of family trauma, environmental disaster, and sexual assault played out on the world stage. The books our writers and editors were drawn to this year include many that illuminate these struggles and inequities, whether in the form of visceral sonnets, lyrical history, or dizzyingly surreal detective yarns. But they also reach past political themes to the most intimate and universal of stories: a cross-continental meditation on transitory love, a warm and funny account of aging, a timeless reinvention of an ancient myth, and an absorbing deconstruction of faith, to name a few. Our list isn’t definitive or comprehensive, but guided by individual interests and tastes. Below, you’ll find essays, poetry, three striking fiction debuts, the first graphic novel to be longlisted for the Man Booker Prize, and more.
For a wellness festival, there was an unexpected amount of talk about the importance of suffering and pain. In one panel about addiction, the ultramarathoner Charlie Engle, who ran 30 marathons in his first three years of sobriety, told the story of his first son being born. “He was gonna save me,” Engle recalled, “and then six days later, after a crack binge, the police are searching my car, and I had to choose between living and dying. And I chose running ... I wanted to pound that part of me out and never visit it again.”
She says that the problem with diabetes is that it’s a silent disease. “Apart from needing to go to the loo a few times in the middle of the night, I experienced zero symptoms. Diabetes had no impact on my life – 99% of the time I forgot I even had it. Perhaps if it had been a disease with more symptoms, I would have been more motivated to do something about it.”
The combination of diabetes and excess body weight puts individuals at high risk of complications. For people who are overweight or obese, a five percent reduction in body weight has been shown to improve glycemic control, lipids and blood pressure and to reduce the need for medication. Weight loss always sound easy: Just eat less and exercise more. If only it were that simple! There are numerous reasons why people struggle to lose weight including mindset, practical problems (like a busy lifestyle or limited access to healthy food) and stress eating. Many benefit from joining a support group, advice from a dietician or using online tracking applications such as the Body
The pain of diabetic nerve damage may respond to traditional treatments with certain medications such as gabapentin (Neurontin), phenytoin (Dilantin), and carbamazepine (Tegretol) that are traditionally used in the treatment of seizure disorders. Amitriptyline (Elavil, Endep) and desipramine (Norpraminine) are medications that are traditionally used for depression. While many of these medications are not indicated specifically for the treatment of diabetes related nerve pain, they are used by physicians commonly.
Maintaining an optimal level of wellness is absolutely crucial to live a higher quality life. Wellness matters. Wellness matters because everything we do and every emotion we feel relates to our well-being. In turn, our well-being directly affects our actions and emotions. It’s an ongoing circle. Therefore, it is important for everyone to achieve optimal wellness in order to subdue stress, reduce the risk of illness and ensure positive interactions.
There is no cure for diabetes. It’s a chronic condition that must be managed for life. This seems odd, given all the modern medical technology we have at our disposal. We can insert heart pacemakers, perform liver transplants, even adapt to bionic limbs, but coming up with a replacement for the islets that produce insulin in the pancreas appears to be out of reach for now. There is something about the pancreas that makes it difficult to fix, which is part of the reason pancreatic cancer remains so deadly.
The consumption of commodified connection doesn’t need to require a small fortune, though. In fact, it can’t, by any of the new, woke definitions of wellness. Hoess would like to get Wellspring up to 4,000 people or so, he tells me, in order to keep the price down. I met two seekers who were there on scholarship, and four who had won a ticket through an Instagram giveaway (people actually do win those things). Hoess contrasted his model with smaller events like the Aspen Ideas Festival (which The Atlantic has long been a partner in producing), which tend to be more expensive at least partly due to scale.
With a smaller food supply and a large influx of worthless and acidic mycotoxins, the organs become weak. When the organs become weak the immune system also becomes weak. And that is the missing link to why the immune system is weak. It is microbes and parasites in the organs which are starting the chain reaction of events that cause type 2 diabetes. The immune system may be attacking its own cells because the immune system has been weakened by microbes and parasites in the organs or the damage may be done by microbes and parasites attacking the organs directly.
Type 1 diabetes is commonly called “juvenile diabetes” because it tends to develop at a younger age, typically before a person turns 20 years old. Type 1 diabetes is an autoimmune disease where the immune system attacks the insulin-producing beta cells in the pancreas. The damage to the pancreatic cells leads to a reduced ability or complete inability to create insulin. Some of the common causes that trigger this autoimmune response may include a virus, genetically modified organisms, heavy metals, vaccines, or foods like wheat, cow’s milk and soy. (4)
Exposure to certain viral infections (mumps and Coxsackie viruses) or other environmental toxins may serve to trigger abnormal antibody responses that cause damage to the pancreas cells where insulin is made. Some of the antibodies seen in type 1 diabetes include anti-islet cell antibodies, anti-insulin antibodies and anti-glutamic decarboxylase antibodies. These antibodies can be detected in the majority of patients, and may help determine which individuals are at risk for developing type 1 diabetes.
At Diabetes Daily, we prefer using the word remission over cure because far too often the state of diabetes returns even with people’s best efforts. Regardless of the definition of a cure, finding a way to live with little to know highs or lows is a worthwhile endeavor. Long-term studies show that even a few years of great blood sugars significantly reduces your long-term risk of complications.
Several studies show laughter is among the best medicines for pain. In Japanese studies of arthritis, people who watched a humorous show reduced their pain by more than 50% for as long as 12 hours. You can watch funny videos or read humorous writing, watch kids or puppies play, or do whatever it takes to make you laugh. You can also laugh for no reason at all. The effect seems to be the same.
Federal health officials said the most likely source of romaine lettuce contamination is from the Central Coastal growing regions in northern and central California. No common grower, supplier, distributor or brand of romaine lettuce has been identified. Several major romaine lettuce producers have agreed to label products with a harvest date by region, and new […]
The symptoms may relate to fluid loss and polyuria, but the course may also be insidious. Diabetic animals are more prone to infections. The long-term complications recognized in humans are much rarer in animals. The principles of treatment (weight loss, oral antidiabetics, subcutaneous insulin) and management of emergencies (e.g. ketoacidosis) are similar to those in humans.
The U.S. Department of Health and Human Services recommends that adults “engage in 150 minutes per week of moderate-intensity or 75 minutes per week of vigorous-intensity aerobic physical activity, or an equivalent combination of the two. Additional recommendation: muscle-strengthening activities that involve all major muscle groups two or more days per week.
Scientists are trying to figure out how to transplant islet cells and then protect them from the patient’s immune system so that long-term immunosuppressive medications aren’t required. Micro encapsulation is an approach scientists are testing to find out if a special coating to the transplanted islets can help the patient avoid rejection of those islets. These coatings let in nutrients to nourish the cells but prevent your body’s immune system from attacking them.
Conventional cow’s milk: Conventional cow’s milk and dairy products should be eliminated, especially for people with type 1 diabetes. Dairy can be a fantastic food for balancing blood sugar if it comes from goat’s, sheep or A2 cows. But stay away from all other forms of dairy because the A1 casein produced by conventional cows will harm the body and trigger an immune response similar to gluten. When buying dairy, only purchase raw and organic products from pasture-raised animals.
McInnes, N., Smith, A., Otto, R., Vandermey, J., Punthakee, Z., Sherifali, D., … Gerstein, H. C. (2017, March 15). Piloting a remission strategy in type 2 diabetes: Results of a randomized controlled trial. The Journal of Clinical Endocrinology and Metabolism, 2016-3373. Retrieved from https://academic.oup.com/jcem/article-abstract/doi/10.1210/jc.2016-3373/3070517/Piloting-a-Remission-Strategy-in-Type-2-Diabetes?redirectedFrom=fulltext
Low blood sugar (hypoglycemia) is common in people with type 1 and type 2 DM. Most cases are mild and are not considered medical emergencies. Effects can range from feelings of unease, sweating, trembling, and increased appetite in mild cases to more serious effects such as confusion, changes in behavior such as aggressiveness, seizures, unconsciousness, and (rarely) permanent brain damage or death in severe cases. Moderately low blood sugar may easily be mistaken for drunkenness; rapid breathing and sweating, cold, pale skin are characteristic of low blood sugar but not definitive. Mild to moderate cases are self-treated by eating or drinking something high in sugar. Severe cases can lead to unconsciousness and must be treated with intravenous glucose or injections with glucagon.
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The scene was otherworldly from the first whiff of essential oils on the premises, the palatial Palm Springs Convention Center and an adjacent resort hotel. Almost all of the attendees (seekers) were under 40 years old, and all looked well below it. Many could not be picked out of a lineup of Lululemon models. At least one actually was. There were celebrity speakers lined up to lend their expertise, including Russell Brand, the comedian turned spirit guide whose face is the poster for the event, and Alicia Silverstone, best known for her starring role in Clueless, who currently sells a line of vitamins out of an expressed concern that all other prenatal vitamins on the market can be harmful to fetuses.
The problem, according to gastroenterologist Hiroshi Mashimo, MD, PhD, is that 70 percent of PPI users take the medications incorrectly. “They aren’t getting proper instruction,” says Mashimo. “Most people equate PPIs as a stronger form of an antacid.” Antacids neutralize acid and are meant to be taken to quell symptoms as they occur. PPIs are part of a more long-term strategy. The right way to take them is in the morning, just before or with breakfast. Food “turns on” the body’s acid-making cells; the medication can then work to stop stomach acid production.
To explain what hemoglobin A1c is, think in simple terms. Sugar sticks, and when it's around for a long time, it's harder to get it off. In the body, sugar sticks too, particularly to proteins. The red blood cells that circulate in the body live for about three months before they die off. When sugar sticks to these hemoglobin proteins in these cells, it is known as glycosylated hemoglobin or hemoglobin A1c (HBA1c). Measurement of HBA1c gives us an idea of how much sugar is present in the bloodstream for the preceding three months. In most labs, the normal range is 4%-5.9 %. In poorly controlled diabetes, its 8.0% or above, and in well controlled patients it's less than 7.0% (optimal is <6.5%). The benefits of measuring A1c is that is gives a more reasonable and stable view of what's happening over the course of time (three months), and the value does not vary as much as finger stick blood sugar measurements. There is a direct correlation between A1c levels and average blood sugar levels as follows.
Diabetes is a serious disease requiring professional medical attention. The information and recipes on this site, although as accurate and timely as feasibly possible, should not be considered as medical advice, nor as a substitute for the same. All recipes and menus are provided with the implied understanding that directions for exchange sizes will be strictly adhered to, and that blood glucose levels can be affected by not following individualized dietary guidelines as directed by your physician and/or healthcare team.
Recent global increase in diabetes, especially type II diabetes, is a product of the global obesity epidemic and attendant increase in Metabolic syndrome. In turn this has fueled an increase in surgical intervention in the form of Bariatric surgery. Diabetes reversal often follows sustained weight loss and indeed a 2014 Cochrane review of such surgeries found diabetes improvement in 5 randomized clinical trials (4). However, depending on the country and insurance plans, such weight loss surgery can be costly. They're also not risk-free with risks varying greatly depending on the person's overall health profile and age as well as skill and experience of the surgeon.
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Body blasting was just one of the hundreds of classes, sessions, panels, talks, and silent dance parties at the inaugural Wellspring wellness festival. Last month some 2,000 mannequin-shaped people floated into Palm Springs, California, for what advertisements promised to be “a first-of-its-kind wellness festival, that will feature over 200 transformational workshops, treatments, and fitness across multiple categories.” The goal was to “provide seekers the tools to learn and take action in real time for a healthier mind in a relational platform.” (Relational platform was a new term to me, but people seemed less than pleased when I used the word conference.)
People with diabetes may also worry about trying new foods; traveling; diabetes complications; the toll the condition takes on their family; and healthcare costs, which are 2.3 times higher than for someone without diabetes. For Sandi, she worries about the cost of medication and, if her kidneys worsen, the possibility that she’ll have to go on dialysis. “That’s a really scary thought,” she says.
Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic disorders in which there are high blood sugar levels over a prolonged period. Symptoms of high blood sugar include frequent urination, increased thirst, and increased hunger. If left untreated, diabetes can cause many complications. Acute complications can include diabetic ketoacidosis, hyperosmolar hyperglycemic state, or death. Serious long-term complications include cardiovascular disease, stroke, chronic kidney disease, foot ulcers, and damage to the eyes.